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    HEMODYNAMICS AND MECHANOBIOLOGY OF ENDOTHELIUM

    edited by Tzung K Hsiai (University of Southern California, USA), Brett Blackman (University of Virginia, USA), & Hanjoong Jo (Georgia Institute of Technology, USA & Emory University, USA)

    Table of Contents (123k)
    Preface (49k)
    Chapter 1: Flow and Atherosclerosis (4,110k)

    The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of fluid dynamics, molecular signaling, genomic approach, tissue engineering, stem cell biology, and microfluidics. This is the first book to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.

     
    Contents:
    • Flow and Atherosclerosis (I Campbell & W R Taylor)
    • Shear Stress-Mediated Signal Transduction (J-I Abe et al.)
    • Endothelial Glycocalyx Structure and Role in Mechanotransduction (J M Tarbell & E E Ebong)
    • Role of Krüppel-Like Factors in Shear Stress-Mediated Vasoprotection (D Kawanami et al.)
    • Rho Family Small GTPases in Shear Stress Signaling (D T Sweet & E Tzima)
    • Nitric Oxide and Endothelial Mitochondrial Function: Implications for Ischemia/Reperfusion (B R Alevriadou et al.)
    • Genomic Approaches to Endothelial Cell Phenotyping (A G Passerini)
    • Endothelial Cell Proliferation and Differentiation in Response to Shear Stress (L-F Zeng et al.)
    • Vascular Differentiation of Stem Cells by Mechanical Forces (T M Maul et al.)
    • Tissue Engineered Blood Vessels: From the Bench to the Bedside and Back Again (Development of a Vascular Conduit for Use in Congenital Heart Surgery) (B S Salameh et al.)
    • Design Implications for Endovascular Stents and the Endothelium (J M Jiménez & P F Davies)
    • Vascular Mimetic Microfluidic Systems for the Study of Endothelial Activation and Leukocyte Recruitment in Models of Atherogenesis (R M Gower & S Simon)
    • Micro Shear Stress Sensors: From In vitro to In Vivo Assessment of Inflammatory Responses (L-S Ai et al.)
     
    Readership: Researchers, academics, postgraduate students in biomedical engineering, biomechanics, cardiology and MEMS/NEMS.
     
     
    380pp    Pub. date: Oct 2010  
    ISBN:   978-981-4280-41-9
    981-4280-41-0
       US$120 / £74

     


    380pp    Pub. date: Oct 2010  
    ISBN:   978-981-4280-42-6(ebook)
    981-4280-42-9(ebook)
       US$156

     


     

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    Updated on 13 February 2012