World Scientific Series in 20th Century Biology - Vol. 1
SELECTED PAPERS OF FREDERICK SANGER
(With Commentaries)
edited by Frederick Sanger & Margaret Dowding (Retired from Medical Res. Council Lab. of Molecular Bio., Cambridge)
This important volume is mainly concerned with the development of methods for "sequencing" — that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
Contents:
- Proteins (19 papers, from 1945 to 1961)
- RNA (8 papers, from
1964 to 1972)
- DNA (21 papers, from 1973 to 1988)
Readership: Biochemists, chemists, molecular biologists and graduate
students in these disciplines.
| 676pp |
Pub. date: Aug 1996 |
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