edited by Chawnshang Chang (University of Rochester, USA)

Table of Contents (42k)
Preface (30k)
Chapter 1: Hormonal Therapy for Prostate Cancer: Clinical and Experimental Evidence (144k)

Prostate cancer is the second leading cause of death in men and its progression is highly dependent on androgens and androgen receptors. However, even with treatment, eventually most prostate cancers progress. Studies of the mechanisms behind this progression leads to advances in treatments for androgen-related diseases. Our book discusses recent prostate cancer research, which includes the following topics: immunotherapy and chemotherapy; radiation, gene, hormonal, and androgen ablation therapies; basic mechanisms behind prostate cancer growth; how mechanisms can be used to treat prostate cancer; and research in newly developed mouse model systems.

This book should be of interest as both a study guide and research reference to students, basic scientists, and clinicians.

• Hormonal Therapy for Prostate Cancer: Clinical and Experimental Evidence (H Miyamoto & C Chang)
• Immunotherapies for Prostate Cancer (K M Harsch et al.)
• Radiation Therapy and Hormonal Therapy for Prostate Cancer (R A Brasacchio)
• Gene Therapy for Prostate Cancer (J A Jiménez et al.)
• Chemotherapy for Prostate Cancer (S K Kulp et al.)
• Chemoprevention in Prostate Cancer (N Fujimoto)
• Neuroendocrine Differentiation and Androgen–Independence in Prostate Cancer (S J Desai et al.)
• Biology of Prostatic Acid Phosphatase and Prostate-Specific Antigen and Their Applications in Prostate Cancer (S Veeramani et al.)
• Epigenetics in Prostate Cancer (J A Karam et al.)
• Significance of 5α-Reductase in Prostate Cancer (J Shimazaki)
• Roles of Vitamin E in Prostate and Prostate Cancer (S Yeh et al.)
• Vitamin D and Prostate Cancer (Y-F Lee et al.)
• Functions of Estrogen Receptor in Prostate and Prostate Cancer (S Yeh et al.)
• Epidemiology of Prostate Cancer (A W Hsing & A Chokkalingam)
• Profiling Gene Expression Changes in Prostate Cancer (P S Nelson)
• Study of Androgen–Androgen Receptor Roles in Prostate Cancer Using Mice Lacking Functional Prostate Androgen Receptor (C-T Wu et al.)
• Capturing Signal Anomalies of Human Prostate Cancer into Mouse Models (H Wu et al.)