STRUCTURE-BASED STUDY OF VIRAL REPLICATION
(with CD-ROM)
edited by R Holland Cheng (University of California, Davis, USA) & Tatsuo Miyamura (The National Institute of Infectious Disease, Japan)
This book addresses the innovative themes in characterizing the cellular membrane platforms and intracellular networking, as well as the architectural aspects of cell compartments mediated by the entry and replication cycles of viruses. The instrumentation of modern molecular and cellular biology provides a potent array of wave packets to image, detect and manipulate major dynamics of macromolecular and subviral assemblies as in the host cellular context.
The book includes case studies presented with highly coherent and structured illuminations, including microscopy, spectroscopy and scanning probes. The compilation and integration of the methodology provides time-resolved observations on the reactivity of structures from near-atomic resolution to various molecular or cellular levels of descriptors. The book provides a broad introduction to the various fascinating virus systems and may be used as an advanced textbook by graduate students in biomedicine. It provides adequate background material to explore further the research problems of epidemics in the 21st century.
Contents:
- Human Rhinovirus Cell Entry and Uncoating (R Fuchs & D Blaas)
-
Virus-Cell Interaction of HCV (H Tani et al.)
- Structure and Dynamics in Viral RNA Packaging (T Dieckmann & M Zumwalt)
- The Assembly of the Double-Layered Capsids of Phytoreoviruses (T Omura et al.)
- Structure and Assembly of Human Herpesviruses: New Insights From Cryo-Electron Microscopy and Tomography (Z H Zhou & P Lo)
- Human Papillomavirus Type 16 Capsid Proteins: Immunogenicity and Possible Use as Prophylactic Vaccine Antigens (T Kanda et al.)
- and others papers
Readership: Microbiologists, virologists, researchers and academics in
cell/molecular biology and structural biology, postgraduates in molecular biology and structural chemistry, educational instructors and industrial researchers.
| 664pp |
Pub. date: Jan 2008 |
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