LECTURE NOTES ON COMPUTATIONAL STRUCTURAL BIOLOGY
by Zhijun Wu (Iowa State University, USA)
While the field of computational structural biology or structural bioinformatics is rapidly developing, there are few books with a relatively complete coverage of such diverse research subjects studied in the field as X-ray crystallography computing, NMR structure determination, potential energy minimization, dynamics simulation, and knowledge-based modeling. This book helps fill the gap by providing such a survey on all the related subjects. Comprising a collection of lecture notes for a computational structural biology course for the Program on Bioinformatics and Computational Biology at Iowa State University, the book is in essence a comprehensive summary of computational structural biology based on the author’s own extensive research experience, and a review of the subject from the perspective of a computer scientist or applied mathematician. Readers will gain a deeper appreciation of the biological importance and mathematical novelty of the research in the field.
Contents:
- X-ray Crystallography Computing
- NMR Structure Determination
-
Potential Energy Minimization
- Molecular Dynamics Simulation
- Knowledge-based Protein Modeling
- Appendices:
- Design and Analysis of Computer Algorithms
- Numerical Methods
Readership: Academics and graduate students in the bioinformatics and
computational biology field, as well as those involved in related industrial research and development.
| 244pp |
Pub. date: Jun 2008 |
|
