edited by Satya Prakash (McGill University, Canada) & Dominique Shum-Tim (McGill University, Canada)

Table of Contents (85k)
Preface (72k)
Chapter 1: Microengineering the Embryonic Stem Cell Environment (3,607k)

This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.

• Stem Cells and Effects of Microenvironment:
  • Microengineering the Embryonic Stem Cell Environment (Yu-Shik Hwang, Bong Geun Chung, Alice Mira Chung and Ali Khademhosseini)
  • Stem Cell Therapy for Ischemic Cardiovascular Diseases: New Insights on Mechanisms and Fate of the Implanted Cells (Nicolas Noiseux, Jean-François Cailhier and Samer Mansour)
  • The Role of Mechanical Forces in the Cardiomyogenic Differentiation of Stem Cells (Daniel Pelaez, Joshua M Hare and Herman S Cheung)
  • Aging and Stem Cell Therapy: A Review and Highlights of Current Controversies (Madhur Nayan, Nina Nouraeyan, Wendy S Chiu and Dominique Shum-Tim)
  • Immunological Basis for Allogeneic Mesenchymal Stem Cell Therapy (Rony Atoui and Ray C J Chiu)
  • Modulation of the Tissue Microenvironment to Enhance the Effects of Cell Transplantation (Paul S Lee and Terrence M Yau)
  • Effect of Nanofibrous Scaffolding on Stem Cell Differentiation and Tissue Formation (Laura A Smith and Peter X Ma)
• Tissue Engineering and Bioengineering of Stem Cells:
  • Genetic Engineering of Human Embryonic Stem Cells: Focusing on Targeted Modification (Katherine M Ruby and Binhai Zheng)
  • Bioartificial Myocardium for the Treatment of Ischemic Heart Disease: First Clinical Experience (Juan C Chachques)
  • Stem Cell Bioengineering and Microencapsulation: Current Perspective and Future Potentials (Arghya Paul, Jasmine Bhathena and Satya Prakash)
• Applications of Cell Therapy — From Bench to Bedside:
  • Fetal-Source Stem Cells (Pai-Jiun Ho, B Linju Yen and Men-Luh Yen)
  • Cartilage Regeneration With and Without Cell Transplantation (Avital Mendelson, Chang Hun Lee and Jeremy J Mao)
  • Transcriptional Regulation and Clinical Applications of Neural Stem Cells (Yi-Chao Hsu and Ing-Ming Chiu)
  • Cellular Cardiomyoplasty: Evidence of Cell Therapy, Mechanisms and Controversies (Adil Al-Kindi, Yin Ge and Dominique Shum-Tim)
  • Enhanced Stem Cell Therapies for Cardio-Pulmonary Diseases (David W Courtman)
  • Stem Cell Therapy for Myocardial Regeneration: The Chinese Experience (Race L Kao, Tuanzhu Ha, Chuanfu Li, Xiang Gao, Fumin Zhang, Zhijian Yiang, Yijiang Chen and Wenzhu Ma)
  • Surgical Autologous Peripheral Blood Stem Cell Implantation for Cardiomyopathy: Bangkok Heart Hospital Experience (Kitipan V Arom and Permyos Ruengsakulrach)