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    MACHINE LEARNING APPROACHES FOR BIOINFORMATICS

    by Rong Yang Zheng (University of Exeter, UK)

    This book covers a wide range of subjects in applying machine learning approaches for bioinformatics projects. The book succeeds on two key unique features. First, it introduces the most widely used machine learning approaches in bioinformatics and discusses, with evaluations from real case studies, how they are used in individual bioinformatics projects. Second, it introduces state-of-the-art bioinformatics research methods. Furthermore, the book includes R codes and example data sets to help readers develop their own bioinformatics research skills. The theoretical parts and the practical parts are well integrated for readers to follow the existing procedures in individual research.

    Unlike most of the bioinformatics textbooks on the market, the content coverage is not limited to just one subject. A broad spectrum of relevant topics in bioinformatics including systematic data mining and computational systems biology researches are brought together in this book, thereby offering an efficient and convenient platform for undergraduate/graduate teaching.

    An essential textbook for both final year undergraduates and graduate students in universities, as well as a comprehensive handbook for new researchers, this book will also serve as a practical guide for software development in relevant bioinformatics projects.

     
    Contents:
    • Introduction to Unsupervised Learning
    • Probability Density Estimation and Applications in Bioinformatics
    • Dimension Reduction — Multidimensional Scaling and Principal Component Analysis, Cluster Analysis
    • Self-Organizing Map
    • Introduction to Supervised Learning
    • Classification and Regression Trees
    • Artificial Neural Networks
    • Vector Machines
    • Hidden Markov Models
    • Feature Selection in Bioinformatics
    • Biological Data Coding
    • Sequence/Structural Bioinformatics Foundation — Peptide Classification
    • Gene Network — Causal Network and Bayesian Networks
    • Metabolomics
    • S-Systems
    • Pathway Recognition
    • Future Directions
    • Appendices:
      • R Codes
      • Study Data Sets
     
    Readership: Final-year undergraduate students, master students, PhD students and researchers in bioinformatics.
     


     
    300pp (approx.)    Pub. date: Scheduled Summer 2010  
    ISBN:   978-981-4287-30-2
    981-4287-30-X
       US$95 / £71

     


     

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    Updated on 20 November 2009