by Eugene J Eisen (North Carolina State University, USA)

Chapter 1: The Beginnings - Ode To A Wee Mouse (58k)

The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and genetics of disease resistance, and have been written by experts in their respective fields.

• The Beginnings: Ode to a Wee Mouse (E J Eisen)
• Testing Quantitative Genetic Selection Theory (E J Eisen)
• Maternal Effects, Genomic Imprinting and Evolution (J Funk-Keenan & W R Atchley)
• Inbreeding and Crossbreeding (G A Brockmann)
• Genotype by Environment Interaction: Lessons From the Mouse (W D Hohenboken)
• Genetics of Growth in the Mouse (J M Cheverud)
• Genetics of Body Composition and Metabolic Rate (L Bünger & W G Hill)
• Genetics of Reproduction (M K Nielsen)
• Genetics of Behavior (R J Hitzemann)
• Genetics of Disease Resistance (S L Ewart & R A Ramadas)
• Genomic Dissection of Complex Trait Predisposition (D Pomp)
• Mouse Mutagenesis (D R Beier)
• Embryo Biotechnologies (C A Pinkert & M J Martin)
• Transgenics (J D Murray & E A Maga)
• The Mouse in Biomedical Research (R B Roberts & D W Threadgill)
• The Mouse Genome Sequencing Project: An Overview (M C Wendl et al.)