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LARGE-SCALE GENOME SEQUENCE PROCESSING
by Masahiro Kasahara & Shinichi Morishita (University of Tokyo, Japan)
Efficient computer programs have made it possible to elucidate and analyze large-scale genomic sequences. Fundamental tasks, such as the assembly of numerous whole-genome shotgun fragments, the alignment of complementary DNA sequences with a long genome, and the design of gene-specific primers or oligomers, require efficient algorithms and state-of-the-art implementation techniques. This textbook emphasizes basic software implementation techniques for processing large-scale genome sequences and provides executable sample programs.
Contents:
- Simple String Search
- Sorting
- Lookup Tables
- Suffix Arrays
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Space-Efficient String Search
- Approximate String Search
- Seeded Alignments
- Whole Genome Shotgun Sequencing. Sequencing
Readership: Course textbook for advanced undergraduate students in computer
science and biology; biotechnology and computer industry and non-experts interested in advanced genome processing algorithms.
| 248pp |
Pub. date: Jul 2006 |
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