This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells.

Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications.

The current volume contains papers by the field’s leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease.

Contents:

• Defining Progenitors Based on Their Expression of Aldehyde Dehydrogenase (R W Storms)
• Fetal Mesenchymal Stem Cells are More Primitive than Adult Mesenchymal Stem Cells (C Götherström et al.)
• The Immunoregulatory Role of Mesenchymal Stem Cells (F Dazzi & J Timoshanko)
• Understanding Cell Migration Through the Paradigm of T-Lymphocyte Homing (V Mirenda & F M Marelli-Berg)
• Blueprint for the Response of Blood and Bone Marrow-Derived Stem Cells and Their Progeny to Hypoxia (S M Watt et al.)
• The Potential of Stem Cells in Tissue Engineering (N D Evans & J M Polak)
• Joint Tissue Engineering (C De Bari et al.)
• Adult Stem Cells as a Treatment for Liver Diseases (N Levicar)
• The Generation of Pancreatic Beta Cells from Stem Cells: Intra- and Extra-Pancreatic Sources (M Brittan et al.)
• Cytokines and Stem Cell Differentiation into Cardiomyocyte Lineage Cells (I Dimarakis)
• Regulatory Networks Controlling Neural Stem Cell Self-Renewal and Differentiation (Y Shi)
• Demyelination as a Therapeutic Target in Spinal Cord Injury (J R Faulkner & H S Keirstead)
• Microchimeric Foetal Stem Cells and Non-Invasive Prenatal Genetic Diagnosis (M A A Mikhail)
• The Role of Stem Cells in Liver and Gastrointestinal Cancer (M R Alison et al.)
• Embryonic Stem Cells: Innovation in Predictive Toxicology (G G Cezar & J Quam)