This book reviews important topics in osteoporosis, with the emphasis on both clinical management and basic research of the disease. From the clinical perspective, topics covering pathogenesis, diagnosis, and treatment of osteoporosis are extensively elaborated. Several more chapters complement clinical overview of osteoporosis, that discuss the effects of nutrition and exercise to bone health, the application of biochemical markers in osteoporosis diagnosis, novel potential drug targets for osteoporosis treatment, and osteoporosis in males and in children. As the prevalence of osteoporosis now reaches epidemiological levels, epidemiology and social impacts of osteoporosis is also reviewed in the book. Basic research on osteoporosis is also highlighted in the book, with a number of chapters dedicated to the review of genetics of osteoporosis, animal models for osteoporosis, and statistical methods in osteoporosis study.

Contents:

• Epidemiology of Osteoporosis (E M C Lau)
• The Social and Financial Costs of Osteoporosis (E King & G Li)
• Pathogenesis of Osteoporosis in Asian and Caucasian Women (Y-B Duan)
• Nutrition and Osteoporosis (R P Heaney)
• Bone Adaptation to Mechanical Loading: How Does Bone Sense the Need for Change to Loading from Exercise? (K S Davision et al.)
• The Diagnosis of Osteoporosis in Postmenopausal Women (M J Barger-Lux & R R Recker)
• Biochemical Markers of Bone Turnover: Assay Methods and Clinical Application (C-Y Guo)
• Bone Marrow Adipogenesis in Osteoporosis (C Wan & G Li)
• Statistical Methods in Osteoporosis Research (Y Lu & H Jin)
• Prevention and Treatment of Postmenopausal Osteoporosis (L A Sun & A Chines)
• Novel Potential Drug Targets for the Anti-Resorptive Treatment of Osteoporosis (J K Xu et al.)
• Male Osteoporosis (L A Sun & A Chines)
• Osteoporosis and Osteoarthritis (Y-Q Zhang)
• Osteoporosis in Pediatrics (H Plotkin & R Lutz)
• Genetics of Osteoporosis (V Dvornyk et al.)
• Pharmacogenetics and Pharmacognenomics of Osteoporosis (D-H Xiong et al.)
• Studying Osteoporosis at the Whole-Genome Level: Problems and Prospects (V Dvornyk et al.)
• Animal Models and Study Design for Osteoporosis Research (H Z Ke & X J Li)
• Prevention and Treatment of Osteoporosis with Trandiational Herbal Medicine (L Qin et al.)
• Appendix: An Introduction to Hologic Technology