edited by Paul David Abel (Imperial College, London) & El-Nasir Lalani (Imperial College, London)

Table of Contents (70k)
Foreword (42k)
Preface (56k)
Chapter 1: Prostate Cancer: Some Clinical and Scientific Dilemmas (126k)

Despite the advent of the genomic era, the perceived benefits of close collaboration between clinicians and scientists are not always realised and the gap between bench and bedside remains. Closer collaboration should expedite advances in treating disease. This important book, with a foreword by Fritz H Schröder, is designed to enhance the relationship between the two communities. It contains data from a multinational authorship, the thirty-eight chapters being written by experts with widely differing training and expectations. Their aim is to facilitate both understanding and in-depth knowledge of their subject. By bridging the gap between clinicians and scientists, the hope is to enhance translational research in their common goal of improving the diagnosis and treatment of prostate cancer, the single most important cancer affecting men.

• Prostate Cancer: Bridging the Gap:
  • Prostate Cancer — Some Clinical and Scientific Dilemmas (P D Abel & E-N Lalani)
• Prostate Cancer: Epidemiology and Genetics:
  • The Epidemiology of Prostate Cancer (D T Bishop)
  • Genetic Aberrations in Prostate Tumours (I C Gray & N K Spurr)
• Prostate Gland: Development Differentiation and Pathology (in Relationship to Malignancy):
  • Development and Differentiation of the Prostate Gland (G R Cunha et al.)
  • Growth Factors in Prostatic Development (A A Thomson et al.)
  • The Prostate and Cancer: An Introduction to Normal Morphology and Histopathology for Research Scientists (C C Coville et al.)
• Molecular and Cell Biology of Prostate Cancer:
  • Cell Lines as Models of Prostate Cancer (S E Mitchell et al.)
  • Ion Channels in Prostate Cancer (M E Laniado et al.)
  • Matrix Metalloproteinases as Potential Targets for Prostate Cancer Therapy (R E Hewitt & A E Yu)
  • Oncogenes and Tumour Suppressor Genes in Prostate Cancer (A Bailey & A F Markham)
  • Emerging Technologies and New Strategies in Prostate Cancer Research (M Ahram & M R Emmert-Buck)
• New Perspectives in Prevention, Control and Clinical Management of Prostate Cancer:
  • Prevention of Prostate Cancer (K B Olson & K J Pienta)
  • Screening for Prostate Cancer (H J de Koning et al.)
  • The Molecular Staging of Prostate Cancer (J M Wells et al.)
  • The Care of Patients with Advanced Hormone Relapsed Prostate Cancer (S Kraus & W Weidner)
  • The Biology and Treatment of Bone Metastases in Prostate Cancer (N W Clarke & L Scott)
  • Prostate Cancer Gene Therapy (N R Ramakrishna et al.)
  • Psychosocial Support of the Prostate Cancer Patient (M A Burke et al.)
  • and other papers